Steal some powerful poisons from Borca, smuggle something from some vampire secret police from one domain to another. You could have a fun campaign around this.
Imagine the weird syncretic religions that creatures with actual souls who keep getting killed and reincarnated would build as they, during their lives, travel from domain to domain, doing whatever it is they can to find whatever there is to help keep them alive just a little longer in the hyper-evil Domains of Dread that they are locked into. This makes Ravenloft a LOT more interesting to me.